10:00 Wyjazd z Krakowa 

13:00–14:00 Obiad

14:00–14:15 Inauguracja LIII Szkoły Zimowej WBBiB 

14:15–16:00 SESJA 1 – Część 1: Molecular Conversations
Decoding the molecular language of life – from structure to systems

14:15–14:35  Andrzej Górecki: The strength of weak interactions in the control of gene expression

14:35–14:55 Anna Wiśniewska-Becker:
Curcumin–lipid interactions in PEGylated vs. conventional liposomes

14:55–15:15 Mateusz Wilamowski: Exploring the structural features of N4BP1 as an RNase associated with mRNA decapping complex

15:15–15:30 Michał Sarna: From titin unfolding to muscle contraction: the effect of mechanical stimulation on sarcomere length and generation of force by cardiomyocytes

15:30–15:45 Grzegorz Szewczyk: Direct measurements of singlet oxygen – from simple solvents to cell cultures

15:45–16:00 Krystian Mokrzyński: Mapping of the triplet excited states of melanins using time-resolved singlet oxygen phosphorescence detection. 

16:00–16:30 Przerwa kawowa

16:30–17:40 SESJA 1 – Część 2: Molecular Conversations
Decoding the molecular language of life – from structure to systems

16:30–16:40 Alicja Martyniak – ALTIUM INTERNATIONAL (Gold Sponsor): Improving T-cell activation and serial killing through metabolic modulation

16:40–17:00 Isabel Fabregat: The TGF-beta pathway as a target to improve immunotherapy in hepatocellular carcinoma (HCC)

17:00–17:20 Agnieszka Łoboda: When a toxic gas becomes protective: hydrogen sulfide in Duchenne muscular dystrophy

17:20–17:35 Anna Grochot-Przęczek: The interplay of NRF2 and miR-34a in vascular pathophysiology

17:40–18:10 FLASH TALK A

• Wojciech Dec – ModelExplorer: A PyMOL plugin for assessing the quality of macromolecular models
• Gabriela Dziurman – Oxygen response to radiotherapy in uveal melanoma murine tumors 
• Milena Cichoń – KEAP1-driven dysfunction of aging endothelial cells
• Piotr Rybczyński – Clozapine regulates neuronal activity-dependent pathways by decreasing AP-1 activity in human neurons
• Rafał Miłodrowski – Social media posts as a source of ecological information over time: using Twitter (X) as a proof of principle

19:00–20:00 Kolacja

20:00–21:00 SESJA PLAKATOWA A

21:00–23:00 Spotkanie integracyjne przy muzyce, kręglach i grach planszowych

8:00–09:00 Śniadanie

9:00–11:00 SESJA 2 – Część 1: Cell-to-Cell Interactions
From single cells to collective behavior-communication and cooperation

9:00–9:25 Józef Dulak: Induced pluripotent stem cells and gene editing in disease modeling and therapy

9:25–9:45 Agnieszka Jaźwa-Kusior: The immunogenic and paracrine roles of senescent endothelial cells in vascular disease

9:45–10:00 Agata Szade: Recombinant G-CSF uncouples neutrophil maturity from canonical progenitor marker expression

10:00–10:20 Martyna Elas: Recent advances in preclinical pO2 imaging

10:20–10:40 Przemysław Mieszko Płonka: Codes of life and codes of biological information

10:40–10:50 Michał Konieczny – CYTO-LOGIC (Silver Sponsor): Flow cytometry in action: Platforms, people and possibilities

11:00–11:30 Przerwa kawowa

11:30–13:00 SESJA 2 – Część 2: Cell-to-Cell Interactions
From single cells to collective behavior-communication and cooperation

11:30–11:40 Mariusz Młyńczak – IKA HABITAT (Silver sponsor): More than a bioreactor – a complete ecosystem for your research

11:40–12:05 Ewa Zuba-Surma: Stem cells as a source of mediators in cell-to-cell communication – role of extracellular vesicles in tissue repair

12:05–12:20 Anna Łabędź-Masłowska: MesoCellA-Ortho as an advanced therapy medicinal product for use in orthopedics – from research to clinical trial

12:20–12:35 Elżbieta Karnas: Polyelectrolytes as effective cryoprotectants for stem fellodermie extracellular vesicles

12:35–12:50 Ilona Ayllot: Investigating the effects of HSPC mobilising factors on the development of GVHD in a haploidentical murine model

12:50–13:00 Weronika Romańska: Brain lipids and cholesterol homeostasis: Physiological interactions and relevance in antipsychotic treatment

3:00–14:00 Obiad

14:00–15:40 SESJA 3 – Część 1: Host–Microbe Interactions
Conflict, coexistence, and communication across biological boundaries

14:00–14:25 Joanna Cichy: Keratinocyte-neuro–immune crosstalk in skin pathophysiology

14:25–14:45 Aleksander Grabiec: Gingival fibroblasts in periodontitis: passive responders or imprinted aggressors?

14:45–15:05 Justyna Karkowska-Kuleta: Moonlighting proteins of Candida fungi in host interactions and contact system binding and activation

15:05–15:20 Michał Bukowski: Natural diversity of staphylococcal lysostaphins: a foundation for novel
antimicrobial drug development

15:20–15:35 Mariusz Madej: Zuzalysin: a giant virus-like proteolytic cage produced by the periodontal pathogen Porphyromonas gingivalis

15:40–16:10 Przerwa kawowa

16:10–16:40 FLASH TALK B

• Rafał Myrczek – Development of a single-cell transcriptomic workflow to study hepatocellular carcinoma initiation in a murine model of Zc3h12a deficiency
• Joanna Król – Zc3h12b destabilizes mRNAs encoding transcriptional regulators of neural development
• Weronika Krzyszczuk – Modification of herpesviruses by gingipains limits their replication
• Izabela Ciastoń – Enzymatically inactive but functional: Proteoliticaly inactive gingipains (piGING) from Porphyromonas gingivalis in esophageal cancer progression
• Alicja Jankowska – Engineering lysostaphins for targeted antimicrobial activity

16:50–17:50 SESJA PLAKATOWA B

18:30–23:00 Uroczysta kolacja i podziękowania dla prof. Andrzeja Kozika za jego wieloletnią pracę na rzecz WBBiB.

8:00–9:00 Breakfast

9:00–10:00 SESJA 3 – Część 2: Host-Microorganism
Interactions. Conflict, coexistence, and communication across biological boundaries

9:00–9:15 Aliaksandr Zhydzetski: The role of the cell wall-binding domain in the activity and specificity
of novel lysostaphins

9:15–9:25 Zuzanna Głowacka-Grzyb: Yin-Yang – the two component system of lysostaphin resistance in Staphylococcus simulans

9:25–9:35 Alicja Frączek: Puzzling contradictions in research on immunomodulatory activity of bacteriocin BacSp222

9:35–9:45 Mariia Melnykova: Oral pathogens induce trained-like immunity in gingival fibroblasts: A novel mechanism of innate immune memory in periodontal disease

9:45–9:55 Maciej Kosiński – BIOMEDICA (Silver sponsor): Nanopore sequencing – technology and applications

10:30–11:00 Przerwa kawowa

10:30–11:45 SESJA 4: Interactions and the Environment
Life in dialogue with its environment – from molecules to ecosystems

10:30–10:50 Ariel Kamiński: Can I eat this? Algae as a valuable component of the human diet

10:50–11:10 Ewa Kowalska: Uncovering the role of FEN1 phosphorylation in Arabidopsis thaliana by the atypical cyclin-dependent kinase CDKF;1

11:10–11:25 Sebastian Pintschner: Cryo-EM of bioenergetic complexes in native membranes

11:25–11:35 Aleksandra Brankiewicz: Hyperforin-mediated mitochondrial uncoupling sensitizes A549 lung cancer cells to everolimus in 2D and 3D models

11:35–11:45 Saravana Kumar: Application and comparison of composites coated with TiO₂ – does it have an impact on Cyanotoxins and Cyanobacterial Blooms?

11:45–12:15 Zamknięcie LIII Szkoły Zimowej WBBiB oraz ogłoszenie z

12:30–13:30 Obiad(opcjonalnie)

14:15 Powrót do Krakowa (zapewniony autobus)